Overview
Rohit Singh is an Assistant Professor in the Departments of Biostatistics & Bioinformatics and Cell Biology at Duke Univ. His research interests are broadly in computational biology, with a focus on using machine learning to make drug discovery more efficient. Currently, he's exploring how single-cell genomics and large language models can help decode disease mechanisms and aid in identifying new targets and drugs. He is the recipient of the Test of Time Award at RECOMB, MIT's George M. Sprowls Award for his PhD thesis in Computer Science, and Stanford's Christopher Stephenson Memorial Award for Masters Research in the same field. In addition to academia, he has experience in the industry.
Current Appointments & Affiliations
Assistant Professor of Biostatistics & Bioinformatics
·
2023 - Present
Biostatistics & Bioinformatics, Division of Integrative Genomics,
Biostatistics & Bioinformatics
Assistant Professor of Cell Biology
·
2023 - Present
Cell Biology,
Basic Science Departments
Assistant Professor in the Department of Electrical and Computer Engineering
·
2023 - Present
Electrical and Computer Engineering,
Pratt School of Engineering
Assistant Professor of Computer Science
·
2024 - Present
Computer Science,
Trinity College of Arts & Sciences
Recent Publications
Comparative analysis of the syncytiotrophoblast in placenta tissue and trophoblast organoids using snRNA sequencing.
Preprint · May 27, 2025 Full text Link to item CiteComparative analysis of the syncytiotrophoblast in placenta tissue and trophoblast organoids using snRNA sequencing
Journal Article eLife · May 27, 2025 The syncytiotrophoblast (STB) is a multinucleated cell layer that forms the outer surface of human chorionic villi. Its unusual structure, with billions of nuclei in a single cell, makes it difficult to resolve using conventional single-cell method ... Full text CiteTracing the Shared Foundations of Gene Expression and Chromatin Structure.
Preprint · April 2, 2025 Full text Link to item CiteRecent Grants
Multiscale Modeling of Influenza Neutralizing Antibody and Fc Effector Biology
ResearchInvestigator · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029Revealing the hidden topologies of the human kinome
ResearchCollaborator · Awarded by Chan Zuckerberg Initiative · 2023 - 2026Revealing the Molecular Architecture of PWS Through Large Language Models for Targeted Drug Purposing
ResearchPrincipal Investigator · Awarded by Foundation for Prader-Willi Research · 2024 - 2026View All Grants
Education, Training & Certifications
Massachusetts Institute of Technology ·
2012
Ph.D.